シラバス参照

基本情報／Basic Information
詳細情報／Detailed Information
授業計画詳細情報／Class Schedule Details

基本情報/Basic Information

開講科目名／Course	糖鎖工学／Biotechnology of Carbohydrates
時間割コード／Course Code	8242000040
ターム・学期／Term・Semester	2024年度／Academic Year　　後期
曜日コマ／Day, Period	他
開講区分／Semester offered	後期／second semester
単位数／Credits	2.0
主担当教員／Main Instructor	吉田孝／YOSHIDA TAKASHI
授業形式／Class Format	講義科目

担当教員情報/Instructor Information

教員名／Instructor	教員所属名／Faculty/Department
吉田孝／YOSHIDA TAKASHI	農学生命科学部／

難易度（レベル）／Level	レベル2
対応するＣＰ／ＤＰ／CP/DP	CP・DP　１　見通す力
授業としての具体的到達目標／Concrete arrival target as the class	Have basic knowledge of the following items (ability to see through). 〇Basic monosaccharide structure. 〇Nomenclature of oligosaccharides and polysaccharides, and the relationship between name and structure. 〇Structure, function, manufacturing method, etc. of oligosaccharides used in health foods, etc. 〇 Sugar chain structure and classification of complex carbohydrates such as glycoproteins. 〇Relationship between microbial and viral infections and cell surface sugar chains.
授業の概要／Summary of the class	There is a widespread misconception that carbohydrates are sweet and cause weight gain. Glycochemistry, which began in ancient times with sugar and starch, has now expanded to a vast range of related fields, including microbial infections and blood types, with the latest theme being the role of sugar chains in molecular recognition. This lecture will begin with basic carbohydrate chemistry and provide an overview of the various structures and functions of carbohydrates, proteins and enzymes related to carbohydrates, and the relationship of sugar chains to life phenomena.
授業の内容予定／Contents plan of the class	This class is an intensive lecture. [Part 1] 1. Basics and nomenclature of carbohydrate chemistry 2. Structure, names, and isomers of monosaccharides 3． Various monosaccharides, sweetness levels, sugar alcohols, etc. 4. Oligosaccharides (1)/Various oligosaccharides Summary and review [Part 2] 5. What is transglycosylation reaction? 6. Oligosaccharide (2), dental caries and sugar transfer reaction 7. Oligosaccharides (3) - Functional oligosaccharides that are not easy on the stomach 8. Polysaccharides, starch and cellulose 9. Cell wall polysaccharides: hemicellulose, pectin, chitin, peptidoglycan 10. Plant biological defense mediated by sugar chains ・Phytoalexins and carbohydrate elicitors Summary and review [Part 3] 11. The world of complex carbohydrates/What are glycoproteins? ・Sugar nucleotides and glycosyltransferases 12. About Asn-linked sugar chains and Ser/Thr-linked sugar chains 13. What is blood type? 　 14. About lectins・Microbial infection and sugar chains・Viral infection and sugar chains 15. Proteoglycans and glycosaminoglycans Summary and review (The progress may vary slightly depending on your level of understanding of the lesson content.)
成績評価方法及び採点基準／A scholastic evaluation method and marking standard	At the end of Parts 1, 2, and 3, there will be a summary and review. The answers to these questions will be evaluated as 100%. Details will be explained in class. (Please note that due to circumstances related to coronavirus infection and prevention, the exam may be conducted remotely. In that case, the exam will be conducted using Teams and Forms, but details will be communicated in advance.) .)
予習及び復習等の内容／Contents such as preparations for lessons and the review	[Preparation] The class begins with a basic lecture on carbohydrates, which will be easier to understand if you have a background in basic organic chemistry, biochemistry, enzyme chemistry, etc. in particular 〇Many structural formulas of carbohydrates appear. Those who have studied the structure of monosaccharides may want to review it. 〇Basic parts of organic chemistry (isomers, chemical bonds, etc.) 〇Cell structures of microorganisms, plants, and animals (intracellular organs, cell walls)
教材・教科書／The teaching materials, textbook	〇Due to the wide range of topics covered, no specific book will be used as a textbook. 〇 Materials used for each class will be distributed via Teams. Distribution of distributed materials to others via the web, email, or other electronic media is strictly prohibited.
参考文献／bibliography	〇I recommend the following books as reference books. “Invitation to Glycoscience” Sankyo Publishing (ISBN 978-4-7827-0519-3) “Science and Engineering of Carbohydrates” Kodansha (ISBN 4-06-139783-4) “Introduction to Glycobiology” Chemistry Doujin (ISBN 978-4759810356) 〇I may use sections related to carbohydrates from Vought's ``Basic Biochemistry, 5th Edition''.
留意点・予備知識／Point to keep in mind, back ground	〇The content of this class is deeply related to biochemistry I/II, applied microbiology, enzyme chemistry, etc. 〇You will develop an intellectual and proactive attitude through the act of writing with your own hands and taking notes. Make sure to take proper notes. 〇Forms will be used for attendance, assignments, etc., and Teams will be used for distribution/collection and class communication. Please install Teams as an app on your own device. In addition, if you transition to remote classes to prevent coronavirus infection, please prepare an internet environment such as Wifi.
授業内容に関する質問・疑義等／Question, doubt about class contents	〇I recommend using Teams chat for individual questions and answers.
Eメールアドレス・HPアドレス／E-mail address, HP address	Email address: ytakashi [at] hirosaki-u.ac.jp Please replace [at] with @.
学問分野1（主学問分野）／Discipline 1	F38:農芸化学およびその関連分野
学問分野2（副学問分野）／Discipline 2	E37:生体分子化学およびその関連分野
学問分野3（副学問分野）／Discipline 3	G43:分子レベルから細胞レベルの生物学およびその関連分野
実務経験のある教員による授業科目について／About the class subject by the teacher with the work experience	なし
地域志向科目／Local intention subject	なし
授業形態・授業方法／Class form, class method	〇This class is an intensive lecture. 〇The lecture format is basically face-to-face. 〇I plan to use Forms to attend classes and exchange assignments. We plan to use Teams for distribution of Forms, other class-related communications, and individual questions and answers. 〇In case of transition to a media class, it will be held on Teams.
科目ナンバー／The subject number
メディア授業による著作物利用の有無について／Whether or not copyrighted works are used in media classes	有／Yes
その他／Others	〇 I will use Teams to communicate with you regarding classes, so please install the app. 〇For information on registering for Teams, etc., please contact Faculty Educational Secretariat. 〇Recording of classes is prohibited.

No.	回（日時）／Time (date and time)	主題と位置付け（担当）／Subjects and instructor's position	学習方法と内容／Methods and contents	備考／Notes
該当するデータはありません

難易度（レベル）／Level	レベル2
対応するＣＰ／ＤＰ／CP/DP	CP・DP　１　見通す力
授業としての具体的到達目標／Concrete arrival target as the class	Have basic knowledge of the following items (ability to see through). 〇Basic monosaccharide structure. 〇Nomenclature of oligosaccharides and polysaccharides, and the relationship between name and structure. 〇Structure, function, manufacturing method, etc. of oligosaccharides used in health foods, etc. 〇 Sugar chain structure and classification of complex carbohydrates such as glycoproteins. 〇Relationship between microbial and viral infections and cell surface sugar chains.
授業の概要／Summary of the class	There is a widespread misconception that carbohydrates are sweet and cause weight gain. Glycochemistry, which began in ancient times with sugar and starch, has now expanded to a vast range of related fields, including microbial infections and blood types, with the latest theme being the role of sugar chains in molecular recognition. This lecture will begin with basic carbohydrate chemistry and provide an overview of the various structures and functions of carbohydrates, proteins and enzymes related to carbohydrates, and the relationship of sugar chains to life phenomena.
授業の内容予定／Contents plan of the class	This class is an intensive lecture. [Part 1] 1. Basics and nomenclature of carbohydrate chemistry 2. Structure, names, and isomers of monosaccharides 3． Various monosaccharides, sweetness levels, sugar alcohols, etc. 4. Oligosaccharides (1)/Various oligosaccharides Summary and review [Part 2] 5. What is transglycosylation reaction? 6. Oligosaccharide (2), dental caries and sugar transfer reaction 7. Oligosaccharides (3) - Functional oligosaccharides that are not easy on the stomach 8. Polysaccharides, starch and cellulose 9. Cell wall polysaccharides: hemicellulose, pectin, chitin, peptidoglycan 10. Plant biological defense mediated by sugar chains ・Phytoalexins and carbohydrate elicitors Summary and review [Part 3] 11. The world of complex carbohydrates/What are glycoproteins? ・Sugar nucleotides and glycosyltransferases 12. About Asn-linked sugar chains and Ser/Thr-linked sugar chains 13. What is blood type? 　 14. About lectins・Microbial infection and sugar chains・Viral infection and sugar chains 15. Proteoglycans and glycosaminoglycans Summary and review (The progress may vary slightly depending on your level of understanding of the lesson content.)
成績評価方法及び採点基準／A scholastic evaluation method and marking standard	At the end of Parts 1, 2, and 3, there will be a summary and review. The answers to these questions will be evaluated as 100%. Details will be explained in class. (Please note that due to circumstances related to coronavirus infection and prevention, the exam may be conducted remotely. In that case, the exam will be conducted using Teams and Forms, but details will be communicated in advance.) .)
予習及び復習等の内容／Contents such as preparations for lessons and the review	[Preparation] The class begins with a basic lecture on carbohydrates, which will be easier to understand if you have a background in basic organic chemistry, biochemistry, enzyme chemistry, etc. in particular 〇Many structural formulas of carbohydrates appear. Those who have studied the structure of monosaccharides may want to review it. 〇Basic parts of organic chemistry (isomers, chemical bonds, etc.) 〇Cell structures of microorganisms, plants, and animals (intracellular organs, cell walls)
教材・教科書／The teaching materials, textbook	〇Due to the wide range of topics covered, no specific book will be used as a textbook. 〇 Materials used for each class will be distributed via Teams. Distribution of distributed materials to others via the web, email, or other electronic media is strictly prohibited.
参考文献／bibliography	〇I recommend the following books as reference books. “Invitation to Glycoscience” Sankyo Publishing (ISBN 978-4-7827-0519-3) “Science and Engineering of Carbohydrates” Kodansha (ISBN 4-06-139783-4) “Introduction to Glycobiology” Chemistry Doujin (ISBN 978-4759810356) 〇I may use sections related to carbohydrates from Vought's ``Basic Biochemistry, 5th Edition''.
留意点・予備知識／Point to keep in mind, back ground	〇The content of this class is deeply related to biochemistry I/II, applied microbiology, enzyme chemistry, etc. 〇You will develop an intellectual and proactive attitude through the act of writing with your own hands and taking notes. Make sure to take proper notes. 〇Forms will be used for attendance, assignments, etc., and Teams will be used for distribution/collection and class communication. Please install Teams as an app on your own device. In addition, if you transition to remote classes to prevent coronavirus infection, please prepare an internet environment such as Wifi.
授業内容に関する質問・疑義等／Question, doubt about class contents	〇I recommend using Teams chat for individual questions and answers.
Eメールアドレス・HPアドレス／E-mail address, HP address	Email address: ytakashi [at] hirosaki-u.ac.jp Please replace [at] with @.
学問分野1（主学問分野）／Discipline 1	F38:農芸化学およびその関連分野
学問分野2（副学問分野）／Discipline 2	E37:生体分子化学およびその関連分野
学問分野3（副学問分野）／Discipline 3	G43:分子レベルから細胞レベルの生物学およびその関連分野
実務経験のある教員による授業科目について／About the class subject by the teacher with the work experience	なし
地域志向科目／Local intention subject	なし
授業形態・授業方法／Class form, class method	〇This class is an intensive lecture. 〇The lecture format is basically face-to-face. 〇I plan to use Forms to attend classes and exchange assignments. We plan to use Teams for distribution of Forms, other class-related communications, and individual questions and answers. 〇In case of transition to a media class, it will be held on Teams.
科目ナンバー／The subject number
メディア授業による著作物利用の有無について／Whether or not copyrighted works are used in media classes	有／Yes
その他／Others	〇 I will use Teams to communicate with you regarding classes, so please install the app. 〇For information on registering for Teams, etc., please contact Faculty Educational Secretariat. 〇Recording of classes is prohibited.

授業情報／Class Information

基本情報/Basic Information

担当教員情報/Instructor Information