基本情報/Basic Information

開講科目名 ／Course	分子病態学講義／Molecular　Pathology (Lecture)
時間割コード ／Course Code	M242000333
ナンバリングコード ／Numbering Code
開講所属 ／Course Offered by	医学研究科／
曜日コマ ／Day, Period	他
開講区分 ／Semester offered	後期／second semester
単位数 ／Credits	2.0
学年 ／Year	1,2,3
主担当教員 ／Main Instructor	若林 孝一／WAKABAYASHI KOICHI
科目区分 ／Course Group	大学院（博士課程）
教室 ／Classroom
必修・選択 ／Required/Elective
授業形式 ／Class Format
メディア授業 ／Media lecture	－

担当教員情報/Instructor Information

教員名 ／Instructor	教員所属名 ／Faculty/Department
森 文秋／MORI FUMIAKI	医学研究科／
若林 孝一／WAKABAYASHI KOICHI	医学研究科／

難易度（レベル） ／Level	Level 5
対応するＤＰ ／DP	DP2  To acquire a broad knowledge of the latest medical science
授業としての具体的到達目標 ／Concrete arrival target as the class	To develop the ability to explain the pathogenesis of neurological diseases at the molecular and genetic level.
授業の概要 ／Summary of the class	In this lecture, students will learn how to analyze the pathogenesis of cranial nerve diseases at the cellular, molecular, and genetic levels, as well as gain knowledge of the major molecular pathological mechanisms (neuronal cell death, inclusion body formation and degradation mechanisms, cell migration, and cell proliferation). In addition, the role of glial cells in the establishment of cranial nerve diseases and lesion repair will be introduced.
授業の内容予定 ／Contents plan of the class	Part  16-17: Animal Models of Neurodegenerative Diseases Part 18-19: Cellular Models of Neurodegenerative Diseases Part 20-21: Mechanisms of protein aggregation in neurodegenerative diseases Part 22-23: Neurodegenerative diseases and ubiquitin-proteasome system Part 24-25: Pathobiochemistry of tauopathies Part 26-27: Pathobiochemistry of synucleinopathy Part 28: Pathobiochemistry of TDP-43 proteinopathy Part 29-30: Efforts toward the treatment of neurodegenerative diseases Examination by oral examination
成績評価方法及び採点基準 ／A scholastic evaluation method and marking standard	Evaluation will be based on questions and answers in class (60 points) and an oral examination (40 points).
予習及び復習等の内容 ／Contents such as preparations for lessons and the review	Preparation and review of academic papers, various materials, and reference books are required.
教材・教科書 ／The teaching materials, textbook	None in particular
参考文献 ／bibliography	References will be provided as needed.
留意点・予備知識 ／Point to keep in mind, back ground	None in particular
授業内容に関する質問・疑義等 ／Question, doubt about class contents	Every Monday from 5-6 p.m.
Eメールアドレス・HPアドレス ／E-mail address, HP address	E-mail: koichi@hirosaki-u.ac.jp http://www.med.hirosaki-u.ac.jp/~neurop/
学問分野1（主学問分野） ／Discipline 1	G46:神経科学およびその関連分野
学問分野2（副学問分野） ／Discipline 2	H48:生体の構造と機能およびその関連分野
学問分野3（副学問分野） ／Discipline 3	H49:病理病態学、感染・免疫学およびその関連分野
地域志向科目 ／Local intention subject	なし
授業形態・授業方法 ／Class form, class method	Lectures are given to small groups of students individually or in seminar format.
科目ナンバー ／The subject number	GM-5-2022-H49
メディア授業による著作物利用の有無について ／Whether or not copyrighted works are used in media classes	無／Nothing
その他 ／Others	None in particular

No.	回（日時） ／Time (date and time)	主題と位置付け（担当） ／Subjects and instructor's position	学習方法と内容 ／Methods and contents	備考 ／Notes
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